Broad Institute of MIT and Harvard Press Releases - EIN Presswire

Published on March 19, 2026 - 14:32 GMT

Mutation reveals connection between schizophrenia and brain circuit needed to incorporate new information

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead people with schizophrenia to struggle with making decisions and, eventually, to lose touch with reality. Neuroscientists from the Broad …

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Published on March 12, 2026 - 15:36 GMT

Stanley Family Foundation renews commitment to accelerate psychiatric research at Broad Institute

The Stanley Family Foundation has renewed its commitment to psychiatric research at the Broad Institute, bringing its total investment to more than $1 billion. This funding, including their newest commitment of $280 million to the Stanley Center for …

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Published on March 4, 2026 - 16:37 GMT

Gut bacteria rewire fat tissue to burn more energy

Most adult body fat consists of white fat cells that store excess calories, but babies are born with stores of brown and beige fat that burn energy to generate heat. Brown fat levels decrease with age, but scientists have long sought to change that, …

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Published on February 27, 2026 - 00:20 GMT

Study reveals genetic balancing act between autoimmunity and cancer risk

An autoimmune disorder that affects the thyroid gland, called autoimmune hypothyroidism (AIHT), is the most common autoimmune disease, yet it remains largely understudied. New research from scientists at Broad Institute, University of Helsinki, and other …

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Published on February 26, 2026 - 00:55 GMT

Free genetic testing program aims to improve medical care across Alabama

An initiative aimed at improving medical care and addressing chronic disease is now underway in Alabama. Catalyst, a precision medicine program led by the Alabama nonprofit Southern Research in collaboration with Broad Clinical Labs at the Broad Institute …

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Published on February 25, 2026 - 21:28 GMT

Scientists sharpen genetic maps to help pinpoint DNA changes that influence human health traits and disease risk

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has created high resolution maps of DNA variant activity, …

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Published on February 22, 2026 - 22:52 GMT

Broad's campus will be open Monday for essential onsite activities only

Broad Institute's gene-editing technologies—CRISPR-Cas9, base editing, and prime editing—are being tested in more than 25 clinical trials to treat or cure leukemias, rare genetic diseases, high cholesterol, and other conditions. NIH-funded discoveries …

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Published on February 10, 2026 - 02:34 GMT

Clinical trial explores whether a genetic test can improve early detection of prostate cancer

A genetic test developed by researchers at Broad Clinical Labs and the U.S. Department of Veterans Affairs (VA) is now enabling a large, nationwide clinical trial aimed at improving health care for men at increased risk of developing prostate cancer, the …

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Published on February 2, 2026 - 22:53 GMT

Feng Zhang inducted into National Inventors Hall of Fame

Broad Institute core member Feng Zhang, along with 15 other innovators, will be inducted into the National Inventors Hall of Fame. In partnership with the United States Patent and Trademark Office, the Hall of Fame will honor the latest class of inductees …

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Published on January 28, 2026 - 20:37 GMT

How genes influence the microbes in our mouths

No matter how much they brush their teeth, some people still get more cavities than others, in part because of differences in genetics and the make-up of the microbes in their mouths. A new study has found human genetic factors that influence the oral …

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Published on January 24, 2026 - 04:04 GMT

AI generates short DNA sequences that show promise for gene therapies

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments that can control gene activity in specific cells. These sequences, called cis-regulatory elements (CREs), make up a large part of …

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Published on January 17, 2026 - 09:14 GMT

Scientists develop molecules that may treat Crohn’s disease

An estimated 3 million Americans have an inflammatory bowel disease (IBD) such as Crohn’s disease or ulcerative colitis. But a lucky few individuals are far less likely to develop IBD because they have a rare variant of a gene called CARD9. This protective …

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Published on January 7, 2026 - 20:55 GMT

Researchers uncover molecular roots of fibrosis or tissue scarring in inflammatory bowel disease

When inflammation in the body goes unchecked, it can cause fibrosis, or tissue scarring that may lead to organ dysfunction or even failure. This can happen in conditions such as inflammatory bowel diseases (ulcerative colitis and Crohn’s disease), chronic …

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Published on December 23, 2025 - 11:12 GMT

High-fat diets make liver cells more likely to become cancerous

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous. The researchers found that in response to a high-fat diet, …

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Published on December 17, 2025 - 23:59 GMT

New study suggests a way to rejuvenate the immune system

As people age, their immune system function declines. T cell populations become smaller and can’t react to pathogens as quickly, making people more susceptible to a variety of infections. To try to overcome that decline, researchers at MIT and the Broad …

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Published on December 10, 2025 - 20:12 GMT

Findings point to path forward for treatment of rare genetic disease

Friedreich’s ataxia (FA) is a rare but devastating genetic disorder. Those with the condition are often diagnosed between 5 and 15 years of age and live only into their 30s or 40s. There is no widely approved treatment that modifies the disease, and …

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Published on December 8, 2025 - 22:59 GMT

NIH Director Jay Bhattacharya visits Broad to engage with scientists about the impact of federally-funded research

Bhattacharya next met with David Liu, Broad core institute member, the Richard Merkin Professor, and Director of the Merkin Institute for Transformative Technologies in Healthcare at Broad. Liu described his team’s efforts to scale up life-saving gene- …

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Published on November 25, 2025 - 11:38 GMT

New AI model could speed rare disease diagnosis

Highlights A new AI model called popEVE can predict how likely each variant in a patient’s genome is to cause disease. The team is testing popEVE in clinical settings to see if it can speed accurate diagnoses of rare, single-variant genetic diseases. The …

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Published on November 20, 2025 - 18:40 GMT

Q&A: How an academic-industry alliance is reshaping the way research can lead to new medicines

Contributions to this project were also made by colleagues in the Broad’s technology platforms, including the Genetic Perturbation Platform, the Center for the Development of Therapeutics, and the Proteomics Platform, and by colleagues in the Broad’s …

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Published on November 20, 2025 - 18:40 GMT

FDA approves first cancer drug based on Broad Institute science

The US Food and Drug Administration has approved the first cancer drug based on discoveries from Broad Institute scientists. The drug, sevabertinib, was developed by Bayer Healthcare Pharmaceuticals in close collaboration with the Broad, and is the first …

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