The Methodology ESEC consists of European experts nominated according to their specific knowledge and strong interest in a particular field. These include statistics, clinical trial methodology, modelling and simulation, real world evidence and artificial intelligence and pharmacogenomics.

EMA's scientific committees and the Scientific Advice Working Party (SAWP) are responsible for appointing the members.

All members have signed a public declaration of interests and confidentiality undertaking form.

Members can join multiple topic areas.