Austin, Texas (CaymanMama.com) — The dreaded swine flu is getting smarter and smarter meaning the medical community has to keep working on ways to battle the strand that has sickened thousands from coast to coast.

Federal health officials confirm that four people in North Carolina have tested positive for a strand of swine flu has developed a resistance to the drug Tamiflu.

This new finding makes the NC cluster the first the U.S. has seen of that many cases so close together.

Health officials say the cases came out of Duke University Medical Center in Durham, North Carolina.

Tamiflu has been touted as one of two of the most effective treatments to fight the swine flu, though health officials are now keeping a closer eye on the warning signs that that virus is beginning to mutate again which would make the drug ineffective.

According to the Associated Press, “About 52 resistant cases have been reported in the world since April, including 15 in the U.S. so far. Officials with the U.S. Centers for Disease Control and Prevention say almost all the U.S. cases have been isolated.”

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