SMi presents the 10th annual conference on ADMET, taking place on the 29th - 30th June 2015 at the Marriott Regents Park Hotel in London, UK

LONDON, UNITED KINGDOM, May 19, 2015 /EINPresswire.com/ -- SMi are thrilled to announce that an exclusive interview with Frame's Director, Gerry Kenna has just been released. Gerry will be speaking on day 2 of the conference and his presentation entitled: Predicting human drug-induced hepatotoxicity will look at topics such as; Iodiosyncratic vs. dose dependent drug hepatotoxicity; drug-related initiating mechanisms and patient-related susceptibility factors; value and limitations of conventional toxicity studies in animals; opportunities provided by transgenic and chimeric humanized animal models; use of in vitro models to de-risk drug related liabilities and challenge of tackling inter-species and inter-individual variability.

When asked: What new developments he envisions for 2015? How can this be actioned sooner rather than later to help lower costs and drug failure rates? He said:

“Two outstanding and inter-dependent gaps for toxicity evaluation are how best to integrate complex data types; and to undertake in vitro/in vivo scaling. This is being tackled by adapting the PBPK based approached used to underpin ADME prediction. Substantial further progress can be expected in the near future.”

To see the full interview visit the website

The 2015 agenda features over 17 case study driven presentations and speakers representing both the pharma and biotech industries, academia, an interactive workshop and a round table discussion discussing and analysing the latest novel technologies being used in the field of Predictive Toxicology and ADME/Tox. With Drug-induced liver and cardiotoxicity still being major causes of drug attrition rates, the programme will feature case studies on the development of human cellular models and state-of-the-art in vitro used to assess toxicity.
In addition to the event, there will be an Interactive Workshop entitled: ADME(T) Strategies for Pharmacological Space Beyond Ro5 and Eukaryotic Enzyme Inhibitors.

Workshop Leader: Constance Höfer, Chief Development Officer, Priaxon AG
08.30am – 12.30pm Wednesday 1st July 2015, Marriott Regents Park Hotel, London, UK
Download the workshop agenda

For further details contact Magdalena Georgieva on +44 (0)20 7827 6148 | mgeorgieva@smi-online.co.uk

Sponsored by: Corning Life Sciences & Sigma-Aldrich

10th Annual ADMET conference
29th & 30th June 2015
Marriott Regents Park Hotel, London, UK
www.admet-event.com/EIN

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About SMi Group:
Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk

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