Most people have experienced distressing events in their lives, such as violence, neglect, or natural disasters. These and other kinds of adverse experiences can have dramatic effects on physical and mental health, yet scientists don’t fully understand how …
Dilated cardiomyopathy (DCM), a leading cause of heart failure, is twice as common in Black individuals as in white individuals. This excess risk is not fully explained by known risk factors such as high blood pressure or socioeconomic barriers to care. …
The 2025 Richard N. Merkin Prize in Biomedical Technology was jointly awarded to Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain in a ceremony and symposium at the Broad Institute on September 30, 2025. The prize, created by the Merkin …
An alliance of scientists at the Broad Institute and Bayer Pharmaceuticals have developed a drug candidate, sevabertinib, that could be a new treatment for a group of lung cancer patients who have few options today. In a new study published in Cancer …
Broad Clinical Labs, in collaboration with Roche Sequencing Solutions and Boston Children’s Hospital, today announced official recognition by Guinness World Records for achieving the fastest DNA sequencing technique to date. Leveraging Roche’s new SBX …
In 2015, an innovative research initiative called Count Me In launched to give every patient with cancer, no matter where they lived, a way to contribute directly to research and help accelerate advances that could one day lead to new treatments. Since …
Broad Institute has appointed Jason Buenrostro as a core institute member. Buenrostro, a leading epigenomics researcher and technology developer, will also join the leadership team of the Epigenomics Program at Broad. Buenrostro is a professor in the …
Researchers at Dana-Farber Cancer Institute and the Broad Institute have developed an artificial intelligence-based diagnostic tool that could transform the way acute leukemia is identified and treated. The tool, called MARLIN (Methylation- and AI-guided …
Although Gail Guo’s parents had no formal scientific training, she fondly recalls their curiosity and frequent chats about research discoveries during her childhood in China. They also told Gail about her aunt who’d studied chemistry and moved to the US to …
Many of you will have heard by now the sad news that David Baltimore passed away on Saturday morning. The New York Times obituary describes David’s roles as one of the greatest scientists and scientific leaders of his generation. His legendary …
In June, Google DeepMind took the wraps off AlphaGenome, its latest machine learning model for biological discovery. While DeepMind's Nobel Prize-winning AlphaFold model focuses on proteins and how they fold, AlphaGenome predicts how genetic variants …
Researchers at Dana-Farber Cancer Institute, Massachusetts General Hospital (MGH), and the Broad Institute have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma (MM) and its precursor conditions. The new method, …
In a pioneering collaboration aimed at transforming pediatric cancer diagnostics and research, Boston Children’s Hospital (BCH), Dana-Farber Cancer Institute (DFCI), and Broad Clinical Labs have announced the formation of BrightSeq (Boston Research in …
Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment — similar to the thin air found at Mount Everest base camp — can protect the brain and restore movement in mice with Parkinson’s-like disease. The new …
A collaborative study between Dana-Farber Cancer Institute and the Broad Institute found that 8.9 percent of children with glioma, the most common form of pediatric brain tumor, have alterations in the fibroblast growth factor receptor (FGFR) family of …
The Broad Institute announced today that Seth Klarman, prominent business leader, investor, philanthropist, and author, will become the next Chair of the Board of Directors, succeeding Eric Schmidt, who has served as Chair of the Board since 2021. Schmidt, …
In May 2025, researchers announced that K.J. Muldoon, a baby boy born without the ability to process dietary protein properly, had become the first person to be treated with a customized gene editing therapy. Based on a technology developed by Broad …
At first, Giulia Monti thought she’d work in another neuroscience lab as a postdoctoral researcher. She had spent the last four years earning her PhD at Aarhus University in Denmark, studying proteins called cargo receptors in Alzheimer’s disease. But then …
The Broad Institute and Bayer have extended their cardiovascular research collaboration of 10 years by an additional five years, further advancing their work in human genomics research in cardiovascular diseases. First launched in 2015 and renewed in 2020, …
Broad Institute researchers have developed a technology that provides new insight into how disruptions in the nucleus of the cell can impact health and disease. The approach, called expansion in situ genome sequencing, allows scientists to sequence DNA and …
