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Human medicines European public assessment report (EPAR): Orladeyo, berotralstat, Angioedemas, Hereditary, Date of authorisation: 30/04/2021, Revision: 5, Status: Authorised

The most common side effects with Orladeyo (which may affect more than 1 in 10 people) are headache, abdominal (belly) pain and diarrhoea. Abdominal pain and diarrhoea, which can occur about 1 to 3 months after starting Orladeyo, get better as treatment continues.

For the full list of side effects and restrictions with Orladeyo, see the package leaflet.

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