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Published on March 6, 2025 - 10:57 GMT

Apoptotic Vesicles Loaded Fibrous Scaffolds Promote Wound Healing

PCL fiber scaffolds loaded with BMSC-derived apoptotic vesicles regulate macrophage polarization via miR-21a-5p to promote wound healing CHINA, March 6, 2025 /⁨EINPresswire.com⁩/ -- A recent study showed that paracrine delivery of miR-21a-5p by bone …

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Published on March 6, 2025 - 10:08 GMT

Melatonin Identified as a Potential Therapeutic Agent For SLC26A2-Related Chondrodysplasias

Targeting ER Stress and Calcium Overload to Restore Skeletal Growth in SLC26A2-Deficient Chondrodysplasias CHINA, March 6, 2025 /⁨EINPresswire.com⁩/ -- Solute carrier family 26 member 2 (SLC26A2) is an SO42− transporter, facilitating the uptake of …

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Published on March 4, 2025 - 10:50 GMT

The Subventricular Zone: A Key to Unlocking Neurological Treatments

SHANNON, CLARE, IRELAND, March 4, 2025 /⁨EINPresswire.com⁩/ -- This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM). The …

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Published on March 4, 2025 - 10:47 GMT

A New Frontier in Cancer Therapy: The Role of Non-Coding RNAs and Oxidative Stress

SHANNON, CLARE, IRELAND, March 4, 2025 /⁨EINPresswire.com⁩/ -- A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the …

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Published on March 4, 2025 - 10:44 GMT

Unlocking the Power of Mechanosensitive Adhesion G Protein-Coupled Receptors in Health and Disease

SHANNON, CLARE, IRELAND, March 4, 2025 /⁨EINPresswire.com⁩/ -- This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and …

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Published on March 4, 2025 - 10:40 GMT

Unraveling the Role of Mitochondrial DNA Integrity in Cardiomyocyte Injury

SHANNON, CLARE, IRELAND, March 4, 2025 /⁨EINPresswire.com⁩/ -- Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light …

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Published on March 4, 2025 - 10:38 GMT

Cardiomyocyte Proliferation: A New Era for Myocardial Repair

SHANNON, CLARE, IRELAND, March 4, 2025 /⁨EINPresswire.com⁩/ -- A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair. The findings underscore the critical …

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Published on March 3, 2025 - 12:40 GMT

Transcriptome and Metabolome Changes in Hepatic Ischemia-Reperfusion Injury

Transcriptomics and metabolomics analysis reveal the characteristic alterations in different stages of hepatic ischemia-reperfusion injury CHINA, March 3, 2025 /⁨EINPresswire.com⁩/ -- Hepatic ischemia-reperfusion injury (IRI) is a common and unavoidable …

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Published on March 3, 2025 - 12:16 GMT

Extracellular Vesicles from Peritoneal Adipose Stem Cells Promote Ovarian Cancer Progression via EGFR-NF-kB Activation

New Study Highlights Role of Adipose-Derived Stem Cells (ADSCs) in Ovarian Cancer Progression and Metastasis CHINA, March 3, 2025 /⁨EINPresswire.com⁩/ -- Ovarian cancer (OC), the most lethal gynecological malignancy, is the fifth leading cause of cancer- …

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Published on March 2, 2025 - 03:28 GMT

Unlocking the Power of DNA Exonucleases and Endonucleases in Immunity

SHANNON, CLARE, IRELAND, March 1, 2025 /⁨EINPresswire.com⁩/ -- A recent review highlights the critical role of DNA exonucleases and endonucleases in immune response and disease management, shedding new light on their potential applications in genomic …

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Published on March 2, 2025 - 03:25 GMT

RGS12: A Key Regulator in Tissue Repair and Human Health

SHANNON, CLARE, IRELAND, March 1, 2025 /⁨EINPresswire.com⁩/ -- A growing body of knowledge highlights the significance of Regulator of G Protein Signaling 12 (RGS12) in maintaining cellular function and tissue integrity. As a key member of the RGS protein …

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Published on March 2, 2025 - 03:23 GMT

TFE3 Unlocks New Avenues for Parkinson’s Disease Treatment

SHANNON, CLARE, IRELAND, March 1, 2025 /⁨EINPresswire.com⁩/ -- This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in counteracting key pathological mechanisms associated with Parkinson’s …

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Published on March 2, 2025 - 03:22 GMT

Highlighting the Role of Fibro-Adipogenic Progenitors in Muscle Regeneration and Degeneration

SHANNON, CLARE, IRELAND, March 1, 2025 /⁨EINPresswire.com⁩/ -- A recent study has shed new light on the role of fibro-adipogenic progenitors (FAPs) in muscle regeneration, fibrosis, and degeneration. These cells play a crucial part in tissue homeostasis, …

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Published on March 2, 2025 - 03:20 GMT

Unraveling the Mechanism Behind Orthodontic Tooth Movement

SHANNON, CLARE, IRELAND, March 1, 2025 /⁨EINPresswire.com⁩/ -- A new study in Genes & Diseases has revealed that heavy mechanical force can decelerate orthodontic tooth movement (OTM) by altering the way periodontal ligament cells (PDLCs) respond to …

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Published on February 25, 2025 - 13:07 GMT

DNA Methylation as a Biomarker for Early Diagnosis of Lung Cancer

Methylation profiles of cancer-related CpG sites in tissue and plasma serve as biomarker for early diagnosis of non-small cell lung cancer. CHONGQING , CHINA, February 25, 2025 /⁨EINPresswire.com⁩/ -- Early diagnosis of lung cancer is a critical priority …

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Published on February 25, 2025 - 12:50 GMT

Single-Cell Transcriptomic Atlas of Chondrocytes Sheds New Light on Osteoarthritis (OA) Mechanisms

Mapping Chondrocyte Diversity in Healthy and Osteoarthritic Cartilage to Uncover New Therapeutic Targets CHONGQING, CHINA, February 25, 2025 /⁨EINPresswire.com⁩/ -- Chondrocytes are specialised cells that are essential for cartilage maintenance and repair …

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Published on February 25, 2025 - 11:21 GMT

The Role of Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction

SHANNON, CLARE, IRELAND, February 25, 2025 /⁨EINPresswire.com⁩/ -- A new review highlights the potential role of single nucleotide polymorphisms (SNPs) in improving the early diagnosis and targeted intervention of coronary microvascular dysfunction (CMD)—a …

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Published on February 25, 2025 - 11:15 GMT

New Advances in Targeted Therapies for PIK3CA-Mutated Cancers

SHANNON, CLARE, IRELAND, February 25, 2025 /⁨EINPresswire.com⁩/ -- A newly published review in Genes & Diseases explores the oncogenic activation of PIK3CA in cancer and highlights emerging targeted therapies designed to improve treatment efficacy …

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Published on February 25, 2025 - 11:14 GMT

Identification of the mTOR Pathway as a Key Target for Diabetic Nephropathy Treatment

SHANNON, CLARE, IRELAND, February 25, 2025 /⁨EINPresswire.com⁩/ -- A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores …

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Published on February 23, 2025 - 21:02 GMT

New Research Identifies FAM20C as a Critical Protein Kinase in Cancer Progression and Disease Mechanisms

A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease progression. SHANNON, CLARE, IRELAND, February 23, 2025 /⁨EINPresswire.com⁩/ -- A new review published in Genes & Diseases …

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