The Infectious Disease Surveillance Systems program administers and maintains the state's secure, web-based electronic disease surveillance system (EpiTrax). It also administers KORDS, the Kansas Online Reporting Disease System, an online portal for healthcare providers to report suspect and confirmed cases of 
COVID-19.

The program also oversees “meaningful use” data interoperability initiatives, including Electronic Laboratory Reporting and Electronic Case Reporting.

EpiTrax is utilized by all local health departments and KDHE. Case information is entered in EpiTrax by both local health departments and KDHE. Disease investigators can access and manage the case records. The system includes an outbreak management module, which facilitates information-sharing between KDHE and local health departments working jointly on outbreak investigations. EpiTrax is used to transmit Kansas reportable disease data to the Centers for Disease Control and Prevention on a weekly basis.