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The growing prevalence of Intrahepatic Cholestasis of Pregnancy is driving the growth of the Cholestasis Market

HYDERABAD, TELANGANA, INDIA, January 12, 2023 /EINPresswire.com/ -- The Cholestasis Market size is valued at $6.22M by 2019 and is anticipated to grow at a CAGR of 4.9% during the forecast period 2020-2025. The Cholestasis Market growth rate is attributed to the changing lifestyle that has altered dietary patterns and results of the use of certain medications that include anabolic steroids, tolbutamide, prochlorperazine, estradio, terbinafine, imipramine, chlorpromazine, birth control pills and cimetidine. Cholestasis is defined as a decrease in bile flow due to impaired secretion by hepatocytes or to obstruction of bile flow through intra-or extrahepatic bile ducts. Therefore, the clinical definition of cholestasis is any condition in which substances normally excreted into bile are retained. The serum concentrations of conjugated bilirubin and bile salts are the most commonly measured. From improvement’s made to enhance the rise in number of product innovations to financial support to the researchers for developing novel interventions is anticipated to propel the Cholestasis Market during the forecast period 2020-2025.

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Key Takeaways

1. North America dominated the Cholestasis Market with a share of% in the year.

2. The factors such as changing lifestyle that has altered dietary patterns and results of the use of certain medications are among the major factor projected to impel the growth of 36% of the Cholestasis Market.

3. An increase in demand for disease-specific novel treatment, vulnerable preterm infants receiving parenteral nutrition and an increase in special designation from the regulatory authorities are the key factors owing to the growth in the segment during the forecast period 2020-2025.

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Segment Analysis

1. On the basis of Cholestasis type, the Intrahepatic Cholestasis segment held the major share of the market in terms of revenue and is estimated to grow with a CAGR of 3.8% during the forecast period. The reason may be attributed to most of the causes of intrahepatic cholestasis being because of both inherited and acquired liver diseases. Another major intrahepatic cholestasis type is Intrahepatic Cholestasis of Pregnancy, where the cells are unable to transport the bile out of the cells normally, which leads to bile acids building up in the blood. Elevated bile acids in the blood are associated with increased risk to the unborn baby.

2. On the basis of age group, the pediatric and adolescent age group is more susceptible to cholestasis owing to the immaturity of the liver. Amongst the various types of cholestasis inherited causes are popular such as the zinc storage disorder. This causes a marked cholestasis jaundice and liver failure found to recur after liver transplantation. The exact cause for this storage disorder remains unknown. Cholestasis in the pediatric and adolescent age groups is believed to rise effectively as children with cystic fibrosis caused by mutation of the CFTR gene are now very common inherited disease, are prominent in individuals surviving into adulthood and is anticipated to further propel the market growth over the projection period of 2020-2025.

3. North America dominated the Cholestasis Market with a share of 36% in 2019. The application of Cholestasis has grown rapidly over the last few years sowing to the increased risk of intrahepatic cholestasis of pregnancy (ICP), relative to women of other ethnicities which continues to expand its market. Incidence of ICP differs between populations, and in some, has changed over time, suggesting both genetic and environmental contributions to aetiology. .

Competitive Landscape:

The top 5 players in the Cholestasis Industry are -

1. Eli Lily and Company
2. Palmetto Health
3. Abbott Laboratories
4. Teva Pharmaceutical Industries Ltd
5. Zydus Cadila

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