Molecular FISH Testing Market to Grow at a CAGR of 7.2% from 2022 to 2027 – Astute Analytica
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Fluorescence in situ hybridization or FISH is a molecular cytogenetic technique performed via molecular probes to analyze chromosomal abnormalities by hybridization.
Factors Influencing the Market
Drivers
Rising cases of genomic abnormalities and cancers will spark unprecedented growth in the global molecular FISH testing market. Additionally, FISH probes find applications in cancer cytogenetics, which will present attractive prospects because governments are pouring high funds into the pharma and biotechnology sectors. Cytogenetic abnormalities impact nearly 2% of pregnancies in women, along with 1% of live births and 6% of stillbirths.
Apart from that, molecular FISH testing offers various benefits, such as high sensitivity and high speed of the FISH technique, which will contribute to market growth.
Restraints
The high cost associated with FISH techniques is expected to complicate the market growth. The process costs around $200,000, which is significantly high for the research labs.
Opportunities
High investments in the pharmacogenomics and pharmaceutical research sector will be opportunistic for the global molecular FISH testing market. For instance, Wellcome Trust and DBT funded the US$ 190 million venture equally with the aim to encourage biomedical research via funding and engagement, thereby driving the growth of the market.
Segmentation Analysis
By Technology, the Cryo FISH segment leads with the highest market share
On the basis of technology, the Cryo FISH segment leads with the highest market share of 28.16% in 2021, while the Q FISH segment will exhibit the highest CAGR of 8.6%. The dominant share of the Cryo FISH segment is linked to the fact that this technique provides efficient spatial resolution, improved detection sensitivity, and enhanced probe accessibility.
By Probe type, the whole chromosome segment leads with the highest market share
On the basis of probe type, the whole chromosome segment holds the highest share of 46.1% in 2021, while the centromeric repeats segment will exhibit the highest growth rate of 7.7% over the forecast period.
The benefits of whole chromosome probes, such as efficient identification of structural chromosomal aberrations are shaping its scope in the market.
Additionally, the high prevalence of chromosome abnormality will present attractive prospects for the centromeric repeats probe because of the fact that these probes fit best for the detection of monosomy, trisomy, and other aneuploidies.
On the basis of cellular stains, the DAPI segment leads with the highest market share
In terms of cellular stains, the DAPI segment leads with the highest market share of 57.5% in 2021, while the others segment will exhibit the highest CAGR of 8.3%. The FISH method is widely used to detect genetic abnormalities, including gene fusions, aneuploidy, and chromosomal loss. The excellent share of the DAPI cellular stain is attributed to the advantages it offers as compared to other stains. For instance, cells stained with DAPI indicate zero ultrastructural alterations, and it also allows the reuse of cells.
Based on application, the cancer research segment leads
By Application, the Cancer Research segment holds the highest share 51.46%, in 2021 and will also exhibit the highest CAGR of 7.7%. FISH test is used to map the genetic material in human cells and can easily show the genetic abnormalities linked to cancer.
Based on End-User, the clinical segment leads with the highest market share
On the basis of end-user, the clinical segment leads with the highest share of 41.9% in 2021, while the companion diagnostics segment is likely to exhibit the highest growth rate of 8.3%. FISH finds a wide range of applications in the clinical research field owing to the fact that this technique is ideal for detecting chromosomal abnormalities associated with cancer.
The companion diagnostic segment will exhibit the highest growth rate because of the fact that FISH is used to analyze congenital diseases, including Down's Syndrome and Edward's Syndrome.
On the basis of region, North America held dominance in the market
Based on region, North America held the largest share of 44% in 2021, while the Asia-Pacific molecular FISH testing market will exhibit the highest growth rate of 9% over the forecast period.
The growth of the North America molecular FISH testing market is attributed to the growing demand for FISH-based diagnostic tests for early cancer diagnosis.
The Asia-Pacific molecular FISH testing market will exhibit the highest growth rate because of the growing senior population in the region, combined with the rising prevalence of infectious diseases, advanced healthcare infrastructure, and growing funding by government bodies.
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Competitors in the Market
Some of the key industry players analyzed in the global molecular FISH testing market include Thermo Fisher, Abbott Laboratories, Agilent, Oxford Gene Technology, ARUP Laboratories, and others.
Market Segmentation
By Technology:
Flow FISH
Q FISH
Immuno FISH
Cryo FISH
Other FISH
By Probe Type:
Locus specific
Centromeric repeats
Whole chromosome
By Cellular Stains:
DAPI (4,6-diamidino-2-phenylindole)
Acridine Orange
Others
By Application:
Cancer Research
o Lung
o Breast
o Bladder
o Haematological
o Gastric
o Prostrate
o Cervical
o Other
Genetic Diseases
Other
By End User:
Research
Clinical
Companion diagnostics
By Region:
North America
The U.S.
Canada
Mexico
Europe
Western Europe
The U.K.
Germany
France
Italy
Spain
Rest of Western Europe
Eastern Europe
Poland
Russia
Rest of Eastern Europe
Asia Pacific
China
India
Japan
Australia & New Zealand
ASEAN
Rest of Asia Pacific
Middle East & Africa
UAE
Saudi Arabia
South Africa
Rest of the Middle East & Africa
South America
Argentina
Brazil
Rest of South America
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Aamir Beg
Astute Analytica
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