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Herpes Vaccine in Development Fails During Clinical Trials; The CBCD Reviews a Report

“Vical Inc. said its genital herpes vaccine didn’t meet the primary endpoint in a Phase 1/Phase 2 clinical trial.” (1)

The public should be aware that it is common for many vaccine candidates to fail during clinical trials.
— Greg Bennett, CBCD

“Infected with a herpes virus? The CBCD recommends taking Gene-Eden-VIR or Novirin.” - Greg Bennett, CBCD

Those who suffer from a genital herpes infection may be disappointed to learn that a potential herpes vaccine under development from Vical Inc. has failed to meet expectations during initial clinical trials. As reported, the vaccine “didn’t meet the primary endpoint of reducing viral shedding.” (1) Vijay Samant, president and CEO of Vical said “We just received the top-line study data and we are disappointed that the vaccines did not meet the primary endpoint. The trial is ongoing and all patients are being followed for safety for 12 months and efficacy for nine months after their final vaccine dose.” (1) Due to the failure of the vaccine candidate, Vical's company shares fell by 47%. As reported, “the biopharmaceutical company’s shares were down 47% to 75 cents in after-hours trading.” (1)

The Center for the Biology of Chronic Disease (CBCD) is also disappointed in the results of the vaccine's clinical trials, since removing herpes from a long list of chronic diseases would be an important step forward for medicine.

However, the public should be aware that it is common for many vaccine candidates to fail during clinical trials. Also, developing an effective, therapeutic vaccine against the herpes virus (HSV-1 and HSV-2) and gaining FDA approval takes time. Until any new anti-herpes vaccine is FDA approved, the CBCD recommends that infected individuals take Gene-Eden-VIR or Novirin, which are natural herpes remedies with a formula backed by clinical studies that followed FDA guidelines.

Click to learn more about herpes symptoms.

The formula of Gene-Eden-VIR and Novirin was tested by Hanan Polansky and Edan Itzkovitz from the CBCD in two clinical studies that followed FDA guidelines. The studies showed that the formula is effective against the herpes family of viruses. The clinical studies were published in the peer reviewed, medical journal Pharmacology & Pharmacy, the first, in a special edition on Advances in Antiviral Drugs. Study authors wrote that, “individuals infected with HSV-1 or HSV-2 … reported a safe decrease in their symptoms following treatment with (the formula of Gene-Eden-VIR and Novirin).” (2) The study authors also wrote that, “We observed a statistically significant decrease in the severity, duration, and frequency of symptoms.” (2)

Gene-Eden-VIR and Novirin can be ordered online on their product websites, here:


Gene-Eden-VIR and Novirin are natural antiviral dietary supplements. Their formula contains five natural ingredients: Selenium, Camellia Sinesis Extract, Quercetin, Cinnamomum Extract, and Licorice Extract. The first ingredient is a trace element, and the other four are plant extracts. Each ingredient and its dose was chosen through a scientific approach. Scientists at polyDNA, the company that invented and patented the formula, scanned thousands of scientific and medical papers published in various medical and scientific journals, and identified the safest and most effective natural ingredients against latent viruses.

To date, Gene-Eden-VIR and Novirin are the only natural antiviral products on the market with published clinical studies that support their claims. Note: Novirin has the same formula as Gene-Eden-VIR. However, it contains higher quality and more expensive ingredients.

It should be noted that “At present, there is no cure for herpes and the infection is life-long. Current therapy for HSV-2 involves daily doses of antiviral drugs which can reduce, but not eliminate, outbreaks and viral shedding, so they can only reduce symptoms but are unable to prevent the spread of the virus.” (3)

What treatments are currently available for those infected with the herpes virus?

“Two types of antiviral treatments against HSV are available: topical and oral. The treatments include penciclovir, acyclovir, famciclovir, and valaciclovir. However, their effectiveness is limited. For instance, a meta-analysis of five placebo-controlled and two dose comparison studies evaluated the effect of aciclovir, famciclovir or valaciclovir on symptoms. The meta-analysis showed that oral antiviral therapy decreases the duration and the associated pain of an outbreak by merely one day.” (2)

The CBCD points out that there are also the natural antiviral products, Gene-Eden-VIR and Novirin, which were designed to help the immune system target the latent HSV in those already infected.

“We believe when a vaccine becomes available that is effective against both the active and latent herpes viruses, it will be a medical breakthrough. However, until such a vaccine hits the market, the CBCD recommends that HSV infected individuals take Gene-Eden-VIR or Novirin against the latent HSV.” – Greg Bennett, CBCD

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(1) Beckerman, J. "Vical’s Herpes Vaccine Didn’t Meet Primary Endpoint" Published June 22, 2015.

(2) Polansky, H., Itzkovitz, E. Gene-Eden-VIR Is Antiviral: Results of a Post Marketing Clinical Study. Published on August 12, 2013.

(3) - "Admedus moves to second dose of Herpes vaccine" Published June 05, 2015

Greg Bennett
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