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Cell Therapy Media, Cell Therapy Kits, Cell Therapy Reagents and Cell Therapy Surface Market Report 2023: Anticipated Approval of Several Cell Therapies to Boost Sector

DUBLIN, March 16, 2023 /PRNewswire/ -- The "Cell Therapy Media, Cell Therapy Kits, Cell Therapy Reagents and Cell Therapy Surface Market: Distribution by Type of Product, Type of Cell Therapy, Scale of Operation, Type of End-User and Key Geographical Regions: Industry Trends and Global Forecasts, 2023-2035" report has been added to's offering.

In the past few years, this therapeutic approach has emerged as one of the key areas of interest in the healthcare sector, given its ability to treat diseases which were previously considered untreatable. Consequently, driven by the benefits offered by cellular therapies and recent approvals granted by regulatory authorities, the demand for cellular therapies has increased considerably; this has led to a rise in the requirement of cell therapy raw materials. Specifically, cell therapy consumables refer to materials that are used in cell therapy manufacturing.

It is worth mentioning that the selection of cell therapy consumables, specifically the cell culture media and supplements, is a crucial step in cell therapy manufacturing as they directly impact the potency and safety of the final product. In this report, we have considered the four predominant types of consumables applicable to cell therapy, namely cell culture media, media kits providing culture media along with the necessary media supplements, reagents and extracellular matrices.

Key Market Insights

Growing Demand for Cell Therapies

Since the development of the first cell therapy, this therapeutic segment has garnered significant attention from researchers and medical practitioners. This can be attributed to the fact that cell therapies have been demonstrated to possess a vast potential in the treatment of rare disorders, which were previously considered incurable.

The popularity of this therapeutic class of products can also be validated from the fact that, since 2019, more than 1,000 clinical trials focused on cell therapies have been initiated. It is also worth mentioning that over 35 cell and gene therapies have already been commercialized, across various geographical locations, till date. Notable examples of recently approved cell therapies include (in reverse chronological order) Breyanzi (June 2022), CarvyktiT (February 2022) and Abecma (March 2021).

Need for High-Quality Cell Therapy Consumables

Driven by the rise in popularity of cell therapies, there is a growth in demand for cell culture media, reagents and surfaces. It is worth mentioning that, amidst the increasing demand for such products, there is a rise in stringency from regulatory authorities to ensure that the quality of raw materials is good. Therefore, to meet the industry needs, cell therapy manufacturers are actively adopting serum free and xeno free products, which are known to reduce the risk of batch-to-batch variability.

Role of Consumables in Commercialization of Cell Therapies

Currently, the marketed cell-based therapies are exorbitantly priced. Even though, with the introduction of automation technologies in cell therapy bioprocessing, the cost and time required for development of such products has reduced significantly, there is still a considerable scope of improvement to make these therapies affordable.

In this context, it is worth mentioning that consumables, including media, reagents and matrices, currently constitute nearly 25% of the overall cost of cell therapy manufacturing. Optimization of raw materials, by streamlining the production processes, can help mitigate wastage and further reduce the manufacturing cost. Moreover, for commercial applications, it is crucial to obtain consistent outcomes during the manufacturing process. Cell culture media, with chemically defined formulation, provides enhanced consistency for production purposes.

Current Market Landscape of Cell Therapy Media, Kits, Reagents and Surfaces

The cell therapy consumable providers market landscape features more than 80 companies, which claim to possess the necessary expertise for manufacturing of over 450 research and / or therapeutic grade raw materials. Some of these players also claim to have developed GMP certified facilities for the production of consumables, which are intended to be used for a range of human cells, including T-cells, stem cells, dendritic cells and NK cells.

Subsequently, cell therapy media market represents majority share (57%) of consumables offered, followed by the share captured by media and supplement kits (26%), extracellular matrices (14%) and cell culture reagents (3%). The ancillary materials offered by these companies are available in various volumes and can be utilized for numerous functions, such as cell proliferation, cell differentiation and cell isolation. Recent developments in this domain indicate that cell therapy consumable providers are actively expanding their capacity and product portfolio in order to accommodate the current and anticipated demand for cell therapies.

Recent Trends Related to Cell Culture Media

In recent years, there has been a considerable rise in regulatory stringency as well as awareness related to disadvantages of using animal-based medica formulations, in the cell therapy domain. Specifically, animal-based media pose an undesirable risk of transfecting infectious agents. This has resulted in a shift towards the higher adoption of chemically defined, animal-component free (serum-free and xeno-free) media, in the cell culture media market. It is worth mentioning that, currently, majority of the cell culture media are being used for the development of stem cell therapies, followed by those intended for T-cell therapies.

Key Drivers in the Cell Therapy Consumables Market

One of the key drivers of the investments in this market is the success of previously commercialized cell therapies. More than USD 35 billion has already invested in cell therapy domain by private investors. In the last few years, cell therapies have offered a relatively more reliable approach for the treatment of rare diseases.

According to a study published in 2019, the prevalence rate of rare diseases is about 263 to 446 million individuals, at any point of time. This necessitates the need for more such life-saving therapies. It is worth highlighting that, by 2030, close to 60 cell and gene therapies are anticipated to receive regulatory approval, further expanding the opportunities associated within the market. These factors will, in turn, lead to a surge in the requirement for cell therapy consumables products, driving significant growth of the domain.

Market Size of the Cell Therapy Consumables Market

Driven by the indubitably rising need for cell therapies, the market for cell therapy media and other consumables is anticipated to grow at a CAGR of 12%, during the period 2023-2035. Specifically, in terms of scale of operation, the demand for consumable products for commercial operations are expected to expand rapidly with the anticipated approval of numerous cell therapies. Additionally, it is worth highlighting that more than 80% of the current market share is captured by players based in North America and Asia-Pacific.

Example Players in the Cell Therapy Consumables Market

Examples of players engaged in this domain (which have also been captured in this report) include BD Biosciences, Bio-Techne, CellGenix, Corning, Irvine Scientific (Acquired by FUJIFILM), Lonza, Miltenyi Biotech, Sartorius, STEMCELL Technologies and Thermo Fisher Scientific.

Scope of the Report

The study presents an in-depth analysis of the various firms / organizations that are engaged in this domain, across different segments.

The report presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain, across different regions. Amongst other elements, the report includes:

  • A detailed assessment of the overall market landscape of companies offering cell therapy consumables, based on several relevant parameters, such as year of establishment, company size (in terms of number of employees), location of headquarters, type of product (kits, media, reagents and extracellular matrices), number and location of consumable facilities, accreditations received, type of end-user (industry and non-industry), media compatibility (serum free , xeno free and both), type of cell therapy (T-cell therapies, stem cell therapies, NK cell therapies, dendritic cell therapies and others), type of function (cell proliferation, cell expansion, cell differentiation, cell activation, cell isolation, cell attachment), kit components (supplements / reagents, growth / induction medium, expansion medium, differentiation medium and others), type of ECM coating (laminin, fibronectin, vitronectin, basement membrane extract and others), type of formulation (powder, liquid, pre-coated cultureware), shelf life (6-12 months, 13-18 months, 19-24 months and 25-36 months), scale of operation (discovery, preclinical, clinical and commercial), application area (research use and therapeutic use), storage temperature (refrigerated, frozen, ultra-low and room temperature), as well as volume of media, reagents and extracellular matrices.
  • A detailed competitiveness analysis of cell therapy consumable providers (kits, media, reagents and extracellular matrices) based on supplier strength (in terms of years of experience and company size), portfolio strength (considering media compatibility, number of unique type of cell therapy, application area, product manufacturing practices and number of consumable facilities) and number of products offered.
  • A detailed brand positioning analysis of prominent industry players (shortlisted on the basis of strength of service portfolio), highlighting the current perceptions regarding their proprietary brands across different consumable classes.
  • Elaborate profiles of key players offering cell therapy consumables (shortlisted on the basis of portfolio strength and number of products offered); each profile includes a brief overview of the company, along with information on its cell therapy consumables focused product portfolio, consumable facilities, recent developments and an informed future outlook.
  • An analysis of recent developments within the cell therapy consumable industry, highlighting information on several partnerships and collaborations, mergers and acquisitions, and expansion initiatives that have taken place within this domain, during the period 2016-2022.
  • A list of over 250 cell therapy developers that are anticipated to partner with cell therapy consumable providers; these players have been shortlisted based on several relevant parameters, such as developer strength (which takes into account a company's size and its experience in this field), pipeline strength and maturity (based on the number of pipeline drugs and affiliated stage of development), and availability of other cell therapy capabilities.
  • An informed estimate of the annual demand for cell therapy consumables (in terms of volume of media required for total number of cells), based on scale of operation and key geographical regions.
  • An in-depth discussion on the upcoming trends and future growth opportunities within the cell therapy consumables market, featuring details related to the significance of automation in cell therapy manufacturing processes and benefits of single use technologies for production of cell therapies.

Frequently Asked Questions

Question 1: What are the factors driving the cell therapy consumables market?

Answer: The growing demand for cell therapies, as a result of the increasing number of commercialized cell therapies and the rise in cell therapy focused clinical trials, is one of the key factors driving the growth of the cell therapy consumables market.

Question 2: How many players are engaged in offering cell culture media for manufacturing of cell therapies?

Answer: Currently, more than 65 companies claim to offer different types of cell culture media for the growth, proliferation, expansion and differentiation of numerous types of cell therapies.

Question 3: How many players are engaged in offering kits for manufacturing cell therapies?

Answer: At present, nearly 40 players claim to offer several types of kits required to manufacture cell therapies. These kits comprise of various key components, including supplements / reagents for isolation, activation and differentiation of cells, growth media, differentiation media and expansion media.

Question 4: How many media products are available in the market for culturing cell therapies?

Answer: The current market features the presence of nearly 260 media products, which can be used for the manufacturing of cell therapies intended for culturing of human cells.

Question 5: What are the partnership and collaboration trends in the cell therapy consumables domain?

Answer: At present, distribution agreements, mergers and acquisitions, and product commercialization agreements are the most common types of partnerships inked by stakeholders engaged in the cell therapy consumables domain.

Question 6: Which geographical segment has the largest market share in the current cell therapy consumables market?

Answer: North America captures the largest share in the current cell therapy consumables market, followed by Asia-Pacific. It is worth mentioning that, within Asia-Pacific, majority of the market share is contributed by China.

Question 7: Which type of product contributes to the largest share of the cell therapy consumables market?

Answer: In 2023, the cell therapy consumables market is expected to be dominated by media. This trend can be attributed to the large quantity of media required for manufacturing of cell therapies.

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