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Hana Biosciences to Present Data From Pivotal rALLy Clinical Trial of Marqibo

December 3, 2009 (FinancialWire) — Hana Biosciences (OTCBB: HNAB), a biopharmaceutical company focused on strengthening the foundation of cancer care, announced that top-line data from its pivotal Phase 2 rALLy clinical trial for Marqibo(R) (vincristine sulfate liposomes injection) for the treatment of adult acute lymphoblastic leukemia in second relapse will be presented at the at the 51st American Society of Hematology annual meeting and Exposition being held in New Orleans, LA, December 5-8, 2009.

Marqibo is a novel, targeted, Optisome-encapsulated formulation of vincristine sulfate, a widely-used chemotherapy, which has shown promising anti-cancer activity in patients with ALL, non-Hodgkin’s lymphoma, Hodgkin’s disease, and melanoma in several clinical trials. Marqibo is designed to enhance the penetration and concentration of vincristine sulfate at sites of active cancer and facilitate dose-intensification compared to standard vincristine formulations. Unlike standard vincristine sulfate, Marqibo has no dose cap. As a result, patients are dosed based on actual patient body surface area thereby allowing them to receive higher doses of Marqibo than they would otherwise receive with standard vincristine sulfate.

Hana Biosciences has received orphan drug and fast track designations for Marqibo for the treatment of adult ALL from the U.S. Food and Drug Administration. Marqibo has also received orphan drug designation for treatment of ALL from the European Medicines Evaluation Agency.

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