A new test for mesothelioma has been developed by researchers at Oxford University. The test involves analyzing a certain type of protein that has been linked to the amount of fluid in a person’s chest cavity. By examining pleural effusion, which is the term used to describe the buildup of fluid in the chest cavity, researchers were able to diagnose mesothelioma. According to researchers, approximately 90 percent of mesothelioma patients have pleural effusion.

Researchers also discovered that levels of the protein mesothelin were almost six times higher in patients with the cancer than in those with secondary lung cancers, and 10 times greater than those with benign conditions.

One researcher, Helen Davies, explained further: "This study suggests a way for clinicians to more readily identify cases of mesothelioma from the start." She added: "Because mesothelioma has a median survival time of 12 months, minimizing the number of invasive procedures and tests patients require is crucial to reduce morbidity and the time they need to spend in hospital. An earlier diagnosis also allows speedier interventions to relieve symptoms as well as initiation of other treatments such as chemotherapy or radiotherapy if appropriate.”

Dr Paul Beckett of the British Thoracic Society said: "A simple test which can exclude the diagnosis without resort to more invasive methods would be welcomed, allowing a more streamlined diagnostic pathway both for those with and without the disease. Such a pathway would be expected to lead to more rapid diagnosis and therefore treatment and perhaps improve the outlook for this disease, as well as avoiding unnecessary tests in those who don’t have mesothelioma."

For those believed to have mesothelioma, a more accurate diagnosis would potentially provide more time for pallative treatment, and an improved quality of life.

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