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CureVac CEO Daniel Menichella Discusses Coronavirus Vaccine Development with U.S. President Donald Trump and Members of Coronavirus Task Force

  • White House today invited representatives of pharmaceutical and biotech companies leading the COVID-19 response effort
  • CureVac currently selecting best vaccine candidates for clinical trials from a variety of constructs
  • GMP-certified production for several million doses available

TÜBINGEN, Germany and BOSTON, March 02, 2020 (GLOBE NEWSWIRE) --  Daniel Menichella, CEO of biopharmaceutical company CureVac, was today invited to the White House to discuss strategies and opportunities for the rapid development and production of a coronavirus vaccine with U.S. President Donald Trump, Vice President Mike Pence, members of the White House Coronavirus Task Force and high-ranking representatives of pharmaceutical and biotech companies working on the outbreak’s response. 

In the discussion, Menichella highlighted the potential of CureVac's mRNA platform for vaccine development based on mRNA technology. "We are very confident that we will be able to develop a potent vaccine candidate within a few months, said CureVac CEO Daniel Menichella. “We can rely on the data of a Phase 1 rabies study in which we were able to immunize all participants with a very low dose. On this basis, we are working intensively to achieve a very low dose for the CoV vaccine as well. In addition, CureVac has a GMP-certified production facility which enables us to produce up to ten million vaccine doses in one production run.” 

CureVac is currently selecting the most suitable vaccine candidates from several constructs based on quality criteria and biological activity. In parallel, the company is coordinating the development of its program with the German Paul Ehrlich Institute (PEI) for accelerated clinical development of these vaccine candidates and is in discussions with other European health authorities. These steps will enable the start of clinical trials in early summer 2020. Two primary study centers have already been identified and are in preparation.

CureVac began development of its first mRNA-based vaccine in 2011 and has extensive experience in this field. The company has received financial support for these developments from the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense, as well as from the Bill and Melinda Gates Foundation and the international vaccine initiative CEPI.

In the Phase 1 rabies study reported in January, CureVac was able to induce immune responses in humans with the extremely low dose of only 1 microgram. If this is shown to apply to a coronavirus vaccine, millions of vaccine doses could potentially be produced at low costs in existing CureVac production facilities.

About CureVac’s platform
CureVac’s platform aims to optimize the properties of mRNA therapeutics and vaccines. The technology can be tailored to induce varying degrees of immune responses against antigens of choice, potentially providing potent prophylactic vaccines for the prevention of infectious diseases, such as rabies, as well as immunotherapies for the treatment of cancer. The technology can also be adapted to avoid such immune activation for purposes of molecular therapies, thereby providing potential new therapeutic modalities for patients suffering from rare diseases.

About CureVac AG
CureVac is a leading clinical stage biotechnology company in the field of messenger RNA (mRNA) technology with 20 years of expertise in developing and optimizing this versatile molecule for medical purposes. The principle of CureVac's proprietary technology is the use of mRNA as a data carrier to instruct the human body to produce its own proteins capable of fighting a wide range of diseases. The company applies its technologies for the development of cancer therapies, antibody therapies, the treatment of rare diseases, and prophylactic vaccines. CureVac has received significant investments, amongst others from dievini Hopp BioTech holding and the Bill & Melinda Gates Foundation. CureVac has also entered into collaborations with multinational corporations and organizations, including Boehringer Ingelheim, Eli Lilly & Co, Genmab, CRISPR Therapeutics, the Bill & Melinda Gates Foundation, and others. CureVac is headquartered in Tübingen, Germany with sites in Frankfurt and Boston, USA.

For more information, please visit or follow us on Twitter at @CureVacAG.

CureVac Media Contact
Thorsten Schüller, Corporate Communications
CureVac AG, Tübingen, Germany
T: +49 7071 9883-1577

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