GENEVA, SWITZERLAND, June 5, 2017 /EINPresswire.com/ -- GAFFI (Global Action For Fungal Infection) today welcomes news from the World Health Organisation (WHO) that it has classed the disease known as chromoblastomycosis - a disfiguring fungal disease of poor farmers in South America, Africa, and Asia - as a neglected tropical disease (NTD).

Chromoblastomycosis also known as chromomycosis, is one of the most prevalent implantation fungal infections in tropical and subtropical regions around the globe. It is a chronic fungal disease of the skin and subcutaneous tissues, first described in the beginning of the 20th century from Brazil, Cuba and Madagascar. It occurs on a worldwide scale, particularly in rural areas and among poor men aged between 30 and 50.

This chronic, mutilating disease is rarely fatal, but gross disfigurement and amputation of limbs is too commonly necessary. Inoculation of the fungus through the skin of plants or soil contamination leads to infection. Thus farmers, animal breeders and foresters are most at risk.

The oil from the Babussu palm tree is used extensively in the beauty industry. However, the hard skin of the tree’s coconut is contaminated by a brown fungus that causes chromomycosis. When the skin is pierced by the tough coconut strands, a slowly progressive infection develops that becomes intensely itchy. Scratching leads to secondary body sites of infection, including the face.

Many other plants carry the causative fungus, which are especially common in Madagascar and certain parts of Brazil. Medicines used for treatment for the majority of the poor are too expensive, and improved treatment availability is essential.

GAFFI’s founding President is Dr David Denning, Professor of Infectious Disease in Global Health at The University of Manchester. He explains: “Most cases of chromo progress, and are rarely curative. Disfigurement and social exclusion are common. Sites most commonly affected are the lower and upper limbs and buttocks. Ear, face, neck and breasts have also been reported. Lesions slowly enlarge becoming verrucose and wart-like. Old lesions can be tumorous or cauliflower-like in appearance.

“Yet this is an occupational disease and could be prevented with the right clothing and protection and good hygiene advice. We have been urging WHO to recognise its impact on these workers and their families, and we are delighted that they have listened to our arguments. Now we need to concentrate our efforts on those companies who buy the oil for their products to persuade them to work with us to reduce this debilitating and horrendous disease.”

De Flavio de Queiros Telles of Department of Public health, Federal University of Parana, Curitiba worked with the Ministry of Health in Brasilia to support the proposal. He declared: “This is a great day for the affected patients – co-ordinated action on prevention, early diagnosis and better therapies will transform lives blighted by these slow growing persistent fungi.”

Professor Lala Soavina Ramarozatovo, Professor of Dermatology at the Medical School of Antananarivo, Madagascar said: “Much remains to be done in our country to fight this infection. Close, complementary collaboration is necessary between dermatologists, general practitioners, biologists, patients themselves and all who can contribute to better knowledge and management of chromomycosis. The Malagasy authorities, now better informed of the magnitude of the problem, have willing supported the GAFFI application to the WHO and facilitated our approach with the support of the partners. They are mobilising support for national and international organizations in the fight against this disease which is a real public health problem in Madagascar.”

For more information and images of the disease please contact Susan Osborne, Director of Communications at The Goodwork Organisation on 07836 229208

Notes to Editors

GAFFI is a registered International Foundation based in Geneva, focussed on four major tasks related to serious fungal infections. These are:
• Universal access to fungal disease diagnostics for serious fungal disease
• Universal access to generic antifungal agents
• Better data on the number and severity of fungal infections
• Health professional education related to better recognition and care for patients with serious fungal disease.

See www.GAFFI.org

In 1914, a young German doctor Max Rudolf, just graduated from Wurzburg Medical School arrived in central Brazil and saw these patients. Using his own microscope from Europe by the bedside, he saw the characteristic fungal cells in skin, and named the infection “Über die brasiliensische Figueira”, later called chromoblastomycosis. The cells are rounded, thick-walled and have a brown pigment.

The global burden is worldwide but the frequency is much higher in tropical and subtropical areas of Africa, Central and South America, Asia and Australia. The exact global burden is unknown but in high endemic areas the incidence can reach 16 cases x 100,000 inhabitants.
The Babassu palm tree fruits are harvested from August to November. Villagers collect the fruits that have naturally fallen down the ground and break them using an axe, hence the nickname Babassu breakers. They get the meat or flesh of these fruits and cold-press them until they get a clear light yellow vegetable oil from them.
More detail on chromoblastomycosis is available here. http://www.life-worldwide.org/fungal-diseases/chromoblastomycosis/

GAFFI application to the WHO here: (we will add to GAFFI page).

WHO STAG report here: http://www.who.int/neglected_diseases/events/tenth_stag/en/

Susan Osborne
Goodwork, Director of Communications
+44 (0)208 747 1488
email us here