AllenInstitute Press Releases

Published on December 23, 2025 - 10:00 GMT

Scientists Develop New Way to 'Listen in' on the Brain’s Hidden Language

Paradigm-shifting technology is changing how researchers do neuroscience SEATTLE, WA, UNITED STATES, December 23, 2025 /⁨EINPresswire.com⁩/ -- Scientists have engineered a protein able to record the incoming chemical signals of brain cells (as opposed to just their outgoing signals). These whisper-quiet incoming messages are the release of the neurotransmitter glutamate, which plays a critical role in how brain cells communicate with one another but until now has been extremely difficult to capture. [ …

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Published on November 17, 2025 - 19:00 GMT

One of the World’s Most Detailed Virtual Brain Simulations is Changing How Scientists Study the Brain

Scientists use supercomputer that can process quadrillions of calculations per second to simulate mouse cortex for “virtual experiments” SEATTLE, WA, UNITED STATES, November 17, 2025 /⁨EINPresswire.com⁩/ -- Harnessing the muscle of one of the world’s fastest supercomputers, researchers have built one of the largest and most detailed biophysically realistic brain simulations of an animal ever. This virtual copy of a whole mouse cortex allows researchers to study the brain in a new way: simulating diseases …

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Published on November 13, 2025 - 13:00 GMT

Scientists unveil the world's most comprehensive AI-powered tool for neuroscience

Massive, first-of-its-kind data resource aims to accelerate medical breakthroughs in brain diseases like Alzheimer’s and Parkinson's SEATTLE, WA, UNITED STATES, November 13, 2025 /⁨EINPresswire.com⁩/ -- Imagine if every neuroscientist in the world could suddenly speak the same language and share their discoveries instantly. Allen Institute researchers and engineers have now unlocked that potential and the vast discoveries it could lead to through the new Brain Knowledge Platform (BKP). This …

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Published on November 5, 2025 - 16:00 GMT

Scientists Complete First Drafts of Developing Mammalian Brain Cell Atlases

New research reveals how early brains form and the critical periods that could help diagnose and treat brain disease SEATTLE, WA, UNITED STATES, November 5, 2025 /⁨EINPresswire.com⁩/ -- A global consortium of scientists has created the first and most detailed “developmental maps” of the mammalian brain (from mouse to human) to date, taking the first critical steps in unraveling the mystery of early brain development and the vital role it plays in health and disease. Life-altering neurodevelopmental …

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Published on October 29, 2025 - 16:00 GMT

How Age Affects Vaccine Responses and How to Make Them Better

Age-related shifts in T cells weaken vaccine response in older adults, but new findings pave the way for next generation of vaccines. SEATTLE, WA, UNITED STATES, October 29, 2025 /⁨EINPresswire.com⁩/ -- As flu season approaches and public health officials roll out their annual push for vaccination, Allen Institute scientists are learning why vaccines can trigger a weaker response in older adults, around age 65, and what can be done to improve them. These insights open the door to designing more effective …

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Published on October 9, 2025 - 12:00 GMT

Scientists Fix Genetic Defect in Mice Tied to Brain Disorders That Include Autism and Epilepsy

Gene therapy successfully reduced epileptic activity, hyperactivity and risk-taking behaviors tied to SYNGAP1-related disorders SEATTLE, WA, UNITED STATES, October 9, 2025 /⁨EINPresswire.com⁩/ -- In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice. These are a class of brain disorders that can lead to severe and debilitating symptoms including intellectual disability, epilepsy, …

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Published on October 7, 2025 - 09:00 GMT

Scientists Create ChatGPT-like AI Model for Neuroscience to Build One of the Most Detailed Mouse Brain Maps to Date

Artificial intelligence reveals undiscovered regions of the brain from large-scale spatial transcriptomics data SEATTLE, WA, UNITED STATES, October 7, 2025 /⁨EINPresswire.com⁩/ -- In a powerful fusion of AI and neuroscience, researchers at the University of California, San Francisco (UCSF) and Allen Institute designed an AI model that has created one of the most detailed maps of the mouse brain to date, featuring 1,300 regions/subregions. This new map includes previously uncharted subregions of the brain, …

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Published on September 24, 2025 - 18:00 GMT

New study reveals rheumatoid arthritis begins long before symptoms, opening door to prevention

The research reveals early-warning signs that could help doctors catch the disease before it starts, potentially saving patients years of pain and disability. SEATTLE, WA, UNITED STATES, September 24, 2025 /⁨EINPresswire.com⁩/ -- Scientists have discovered that rheumatoid arthritis (RA) doesn’t start when the pain begins. It silently starts years earlier. RA is a debilitating autoimmune disease that causes painful joint inflammation and damage. The new research reveals that people at risk for RA experience …

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Published on September 15, 2025 - 09:00 GMT

Scientists shoot lasers into brain cells to uncover how illusions work

Supported by the Allen Institute’s OpenScope program, the findings could help us better understand neuropsychiatric disorders like schizophrenia SEATTLE, WA, UNITED STATES, September 15, 2025 /⁨EINPresswire.com⁩/ -- An illusion is when we see and perceive an object that doesn’t match the sensory input that reaches our eyes. In the case of the image attached, the sensory input is four Pac Man–like black figures. But what we see or perceive is a white square—i.e., the illusion. In a new study published in …

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