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There were 2,126 press releases posted in the last 24 hours and 438,071 in the last 365 days.

Broad Institute of MIT and Harvard Press Releases

149 Press Releases

Published on June 27, 2024 - 23:12 GMT

A therapy candidate for fatal prion diseases turns off disease-causing gene

Prion diseases lead to rapid neurodegeneration and death and are caused by misshapen versions of the prion protein in the brain. There are currently no treatments, but researchers from the Whitehead Institute for Biomedical Research and Broad Institute of …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on June 25, 2024 - 20:33 GMT

Gut microbiome changes align with increased risk of type 2 diabetes

The largest and most ethnically and geographically comprehensive investigation to date of the gut microbiome of people with type 2 diabetes (T2D), prediabetes, and healthy glucose status has found that specific viruses and genetic variants within bacteria …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on June 18, 2024 - 20:34 GMT

Simple test for flu could improve diagnosis and surveillance

Fewer than one percent of people who get the flu every year get tested in part because most tests require trained personnel and expensive equipment. Now researchers have developed a low-cost paper strip test that could allow more patients to find out which …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on June 14, 2024 - 22:39 GMT

Some CRISPR screens may be missing cancer drug targets

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or “cancer …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on June 11, 2024 - 19:30 GMT

#WhyIScience Q&A: A biochemist uses mass spectrometry to find proteins involved in cancer

When Moe Haines first moved from Beirut, Lebanon to the United States for college, his goal was to earn a degree in pharmacy. Haines was the first person in his family to pursue science, and most people he knew with similar interests had chosen a career in …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on June 10, 2024 - 17:17 GMT

Improved prime editing system makes gene-sized edits in human cells at therapeutic levels

Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applications …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on May 16, 2024 - 18:00 GMT

New gene delivery vehicle shows promise for human brain gene therapy

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on May 14, 2024 - 12:45 GMT

Merkin Prize in Biomedical Technology awarded to F. William Studier for development of widely used protein- and RNA-production ...

“The T7 system has been influential in biomedicine and has had important clinical implications for many years, but Bill Studier’s contribution to the field has really not been as celebrated as it ought to be,” said Harold Varmus, chair of the Merkin Prize …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on May 9, 2024 - 12:30 GMT

Calico and Broad Institute extend collaboration, adding focus on age-related neurodegeneration

In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks. We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap). Broad …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on May 2, 2024 - 14:00 GMT

#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Tell us a bit about your research. Why are you studying autopsy samples from cancer patients? Cancers can develop many paths to drug resistance and it’s important to understand how every cell in a cancer develops resistance. If you have a primary tumor …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on May 1, 2024 - 20:02 GMT

Scientists work out the effects of exercise at the cellular level

The health benefits of exercise are well known but new research shows that the body’s response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists from across the United States has found that …

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Published on April 25, 2024 - 15:16 GMT

A new viral surveillance system in West Africa is showing the world how to prevent the next pandemic

“Pardis and Christian have created an environment where we can collaborate closely with our colleagues in West Africa, which gives us a deep understanding of what the current system looks like and where tools can fill in the gaps,” said Colby Wilkason, …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on April 18, 2024 - 13:56 GMT

Scientists uncover 95 regions of the genome linked to PTSD

In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person’s quality of life. About 6 percent of people who experience trauma develop the disorder, but scientists …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on April 2, 2024 - 15:00 GMT

Scientists link certain gut bacteria to lower heart disease risk

Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers at the Broad Institute of MIT and Harvard along with Massachusetts General Hospital has …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 26, 2024 - 18:56 GMT

Ancient DNA reveals possible origin of a racial/ethnic disparity in a childhood cancer

People who identify as Hispanic/Latino have the highest risk of a blood cancer called acute lymphoblastic leukemia (ALL) compared to other populations in the US, with 40 percent more Hispanic/Latino children being diagnosed than non-Hispanic white children …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 25, 2024 - 17:32 GMT

#WhyIScience Q&A: A cell biologist now helps recent college graduates launch their scientific careers

After watching the Jane Goodall news segment, how did you make your way to pursuing higher education? In my high school biology class, we watched a video of a cell dividing and I remember thinking, “How is that possible? How does that happen?” It was just …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 22, 2024 - 10:11 GMT

Messenger RNAs with multiple “tails” could lead to more effective therapeutics

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, are also being developed …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 20, 2024 - 18:14 GMT

Spatial study of lung cancer reveals immune markers of response to immunotherapy

Most patients with cancer who are treated with immunotherapies called PD-1 inhibitors don’t respond to the treatments and many researchers have been trying to figure out why by studying immune cells in human tumors. Scientists at the Broad Institute of MIT …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 19, 2024 - 15:00 GMT

Researchers roll out a more accurate way to estimate genetic risks of disease

A new scoring approach featured in Cell Genomics and developed by researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) uses a comprehensive approach to generate more accurate and informative PRSs. Aptly named …

Distribution channels: Healthcare & Pharmaceuticals Industry
Published on March 14, 2024 - 19:29 GMT

Scientists generate new targeted protein degradation system that tunes a cell’s own proteins

Researchers studying the role of proteins in health and disease use experimental tools that inactivate proteins, destroy them, or prevent them from being made in cells. In one approach, they mark targeted proteins with “destroy me” tags that work with …

Distribution channels: Healthcare & Pharmaceuticals Industry

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