Apoptosis - The “New and Exploding” Area of Biological Research

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Caspase Independent Cell Death (CICD), a novel method, triggers death of cancerous cells by alerting the human immune system by releasing inflammatory proteins.

Shortcomings in apoptosis can lead to cancer, auto immune diseases and viral infections while excessive apoptosis can cause or worsen neurodegenerative ailments, AIDS and ischemic diseases.”
— Anasuya Vemuri

HYDERABAD, TELANGANA, INDIA, September 7, 2017 /EINPresswire.com/ -- Apoptosis market research report by RI Technologies gives an insight into Apoptosis Mechanism, by Molecular Pathways – Caspase Activators and Inhibitors, Protease/Proteasome Inhibitors, Bcl-2 Modulators and p53 Modulators. The study also focuses on major diseases for which the treatment is based on apoptosis comprising Cancer, Neurodegenerative Diseases, Cardiovascular Diseases and other apoptosis based diseases including HIV infection, Organ Transplant Rejection and MODS. Business profiles of 47 major companies are discussed in the report. The report serves as a guide to global apoptosis market, as it covers more than 550 companies that are engaged in apoptosis research, testing and supply of products and services. Major Contract Research Organizations and Universities serving apoptosis market are also covered in the Corporate Directory section of this report. Information related product developments, partnerships, collaborations, and mergers and acquisitions are also covered in the report. Compilation of Worldwide Patents and Research related to Apoptosis is provided.

Over the past few years, availability of apoptosis related products (drugs, kits and reagents) has increased enormously. Global market for apoptosis related products is expected to grow at a high CAGR of about 30% through 2022, and the high growth is owing to increasing evidence of the role of apoptosis in mechanism of action for large number of diseases such as Cancer; Neurodegenerative Diseases including Alzheimer's, Parkinson's, Multiple Sclerosis and Rheumatoid Arthritis; Cardiovascular Disease; and other apoptosis based diseases including organ transplant rejection and HIV infection. Cancer research has delivered outstanding progress in understanding the biology and genomics of cancer, in the last decade. Foremost of these progress areas is the recognition of apoptosis and its regulatory genes that have an effect on melanoma. In return, other oncogenical changes stimulate apoptosis and override apoptosis during multistage carcinogenesis by making selective pressures. Apoptosis associates cancer therapeutics with cancer genetics by providing conceptual structure, as well as similar changes that suppress apoptosis during tumor development.

The growth of multi-cellular organic structures and their protection hinges upon a complex interaction between the cells constituting the organism. The process, now and then’ even takes the form of selfless actions of individual cells in support of the living being in its entirety. During growth more number of cells than necessary are generated, which ultimately experience programmed cell death and thus, facilitates in carving out several organs and tissues.
A predominantly educative illustration for connotation of programmed cell death during the process of growth of an animal is the creation of free and separate numbers of cells by death of cells in enormous numbers in the ‘inter-digital Mesenchymal tissue’ Other examples of programmed cell death, include the growth of the brain and the reproductive organs. During the growth of brain at least fifty percent of neurons generated initially will die in subsequent stages, when the growth of the brain is complete. Moreover, cells of a mature living organism regularly experience cell death as part of their functioning and the homeostasis or equilibrium is maintained in terms of constant number of cells through their propagation.

Taking into account all aspects, it can be stated that as apoptotic processes play a vital role in the growth, differentiation, propagation, homeostasis, controlling and working of the immune system, elimination of defective and dangerous cells, they have comprehensive biological significance. Any dysfunction or defective management of apoptotic process manifests in a range of pathological conditions. Shortcomings in apoptosis can lead to development of cancer, auto immune diseases and spread of viral infections. On the other hand, excessive apoptosis can cause or worsen ‘neurodegenerative’ ailments, AIDS and ischemic diseases.

Apoptosis report is an ideal research tool providing strategic business intelligence to the corporate sector. This report may help strategists, investors, laboratories, pharmaceutical companies, contract research organizations, biotechnology companies and drug approval authorities in--
 Gauging Competitive Intelligence
 Identifying Key Growth Areas and Opportunities
 Understanding Geographic Relevance to Product
 Knowing Regional Market Sizes and Growth Opportunities and Restraints
 Keeping Tab on Emerging Technologies
 Equity Analysis
 Tapping New Markets

Analytics and data presented in this report pertain to several parameters such as –
 Global and Regional Market Sizes, Market Shares, Market Trends
 Product (Global and Regional) Market Sizes, Market Shares, Market Trends
 Technology Trends
 Corporate Intelligence
 Key Companies by Sales, Brands, Products
 Consumer Behavioral Patterns
 Other Strategic Business Affecting Data


RI Technologies believes in pure research that will trigger action for immediate customer needs rather than plain reporting of data.

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